The University of Dundee Drug Discovery Unit (DDU) has been awarded “Project of the Year, 2014” by the non-for profit organisation, Medicines for Malaria Venture (MMV). The award is for “DDD107498 – The Compound with Muscle”, developed by a team in the DDU in collaboration with MMV and their network of partner organisations. This exciting antimalarial compound has been selected as a preclinical candidate by MMV and subsequently partnered with the pharmaceutical company Merck Serono.
DDD107498 was reported in Nature, Vol. 522, p315-320 as a compound with a potent and novel spectrum of antimalarial activity against multiple life-cycle stages of the Plasmodium parasite, with good pharmacokinetic properties and an acceptable safety profile.
The MMV project of the year award is an internal MMV award, established in 2001 to recognise the most exciting drug discovery and development projects in the MMV portfolio and applaud the scientific partners involved. The project of the year is selected by MMV’s independent Expert Scientific Advisory Committee at the end of each year. MMV projects are subject to rigorous industry–style management and the project of the year is one that meets our demanding product profiles, has made rapid progress and has achieved its milestones.