Publications | Drug Discovery Unit

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May 2010

Nuclear DBF-2-related kinases are essential regulators of cytokinesis in bloodstream stage Trypanosoma brucei.

Publication Date:
14 May 2010

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Apr 2010

N-myristoyltransferase inhibitors as new leads to treat sleeping sickness.

Publication Date:
01 Apr 2010

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Dec 2009

Chemical validation of trypanothione synthetase: a potential drug target for human trypanosomiasis.

Publication Date:
25 Dec 2009

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Investigation of Trypanothione Reductase as a Drug Target in Trypanosoma brucei

Publication Date:
01 Dec 2009

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Sep 2009

The Emerging Academic Drug-Discovery Sector

Publication Date:
01 Sep 2009

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Aug 2009

Improved tricyclic inhibitors of trypanothione reductase by screening and chemical synthesis.

Publication Date:
04 Aug 2009

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Synthesis and evaluation of 1-(1-(Benzo[b]thiophen-2-yl) cyclohexyl)piperidine (BTCP) analogues as inhibitors of trypanothione reductase.

Publication Date:
03 Aug 2009

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Jul 2009

One scaffold, three binding modes: novel and selective pteridine reductase 1 inhibitors derived from fragment hits discovered by virtual screening.

Publication Date:
23 Jul 2009

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Mar 2008

Lessons learnt from assembling screening libraries for drug discovery for neglected diseases.

Publication Date:
14 Mar 2008

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Dec 2007

Target Assessment for Antiparasitic Drug Discovery

Publication Date:
01 Dec 2007

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