The Innovative Targets portfolio (ITP) encompasses high quality projects in any therapeutic area where there is a clinical unmet need. We seek to identify novel therapeutic targets and mechanism of disease with the aim of developing new, innovative treatments for a broad range of diseases. The output from this portfolio is data packages that describe partially de-risked novel drug targets, plus pharmacological lead compounds with supporting data in an animal and/or tissue model of disease.
We select our targets from a wealth of world-class academic research globally. Core funding allows us to take on projects which are traditionally perceived to be risky or difficult due to the unpredictable tractability of many targets, especially complex cell-based mechanisms.